This report comprises the content that experts on adolescent substance use and prevention and early intervention wish to communicate to members of the public. Together, these points represent the “untranslated story” of adolescent substance use. Because Screening, Brief Intervention, and Referral to Treatment (SBIRT) is recognized as an important component of a comprehensive approach to addressing adolescent substance use, this story includes a subchapter on SBIRT. This distillation of the expert view was generated through the analysis of 10 one-on-one, one-hour phone interviews with experts; a review of materials from relevant academic literatures; and a feedback session conducted with adolescent substance use experts to verify and refine the elements of the story.